RNA preprints: W25/2018

Colonic Epithelial miR-31 Associates with the Development of Crohn’s Phenotypes. Benjamin P Keith, Jasmine B Barrow, Nevzat Kazgan, Neil D Shah, Greg R Gipson, Wendy A Pitman, Shruti J Saxena, Elisabeth A Wolber, Matthew S Schaner, Michelle Hoffner O’Connor, Omar K Tradd, Matthew Kanke, Takahiko Toyonaga, Nicole Chaumont, Timothy S Sadiq, Mark J Koruda, Paul A Cotney, Nancy Allbritton, Dimitri G Trembath, Francisco Sylvester, Terrence S Furey, Praveen Sethupathy, Shehzad Z Sheikh

Plasmodium male gametocyte development and transmission are critically regulated by general and transmission-specific members of the CAF1/CCR4/NOT complexKevin J. HartJenna OberstallerMichael P. WalkerAllen M. MinnsMark F. KennedyIan PadykulaJohnAdamsScott E. Lindner

Ligand Modulates Cross-Coupling between Riboswitch Folding and Transcriptional Pausing. Julia R WidomYuri A NedialkovVictoria RaiRyan HayesCharles L Brooks IIIIrina ArtsimovitchNils GWalter

Transcription initiation defines kinetoplast RNA boundaries. Francois M. Sement, Takuma Suematsu, Liye Liye Zhang, Tian Yu, Lan Huang, Inna Aphasizheva, Ruslan Aphasizhev

A new cancer-testis long noncoding RNA, the OTP-AS1 RNA. Iulia K. Karnaukhova, Dmitri E. Polev, Larisa L. Krukovskaya, Alexei E. Masharsky, Olga V. Nazarenko, Andrei A. Makashov, Andrei P. Kozlov

Single-cell level transcriptome of the maize pathogenic fungi cochliobolus heterostrophus race O in infection reveal the virulence related genes, and potential circRNA effector. Jie Chen, meng wang, shaoqing wang, jianan sun, yaqian li, kai dou, zhixiang lu

Two-step binding kinetics of tRNAGly by the glyQS T-box riboswitch and its regulation by T-box structural elements. Jiacheng Zhang, Bhaskar Chetnani, Eric D. Cormack, Wei Liu, Alfonso Mondragon, Jingyi Fei

Developmental genetics of corolla tube formation: role of the tasiRNA-ARF pathway. Baoqing Ding, Rui Xia, Qiaoshan Lin, Vandana Gurung, Janelle M. Sagawa, Lauren E. Stanley, Matthew Strobel, Pamela K. Diggle, Blake C. Meyers, Yao-Wu Yuan

Understanding RNP remodelling uncovers RBPs functionally required for viral replication. Manuel Garcia-Moreno, Marko Noerenberg, Shuai Ni, Aino I Jarvelin, Esther Gonzalez-Almela, Caroline Lenz, Marcel Bach-Pages, Victoria Cox, Rosario Avolio, Thomas Davis, Svenja Hester, Thibault JM Sohier, Bingnan Li, Miguel Angel Sanz, Luis Carrasco, Emiliano P Ricci, Vicent Pelechano, Bernd Fischer, Shabaz Mohammed, Alfredo Castello

Exploration of miRNA-mediated fertility regulation network of cytoplasmic male sterility during flower bud development in soybean. Xianlong Ding, Hao Zhang, Hui Ruan, Yanwei Li, Linfeng Chen, Tanliu Wang, Ling Jin, Xiaoqiang Li, Shouping Yang, Junyi Gai

Precise tuning of gene expression output levels in mammalian cells. Yale S. Michaels, Mike B Barnkob, Hector Barbosa, Toni A Baeumler, Mary K Thompson, Violaine Andre, Huw Colin-York, Marco Fritzsche, Uzi Gileadi, Hilary M Sheppard, David JHF Knapp, Thomas A Milne, Vincenzo Cerundolo, Tudor A Fulga

S-CAP extends clinical-grade pathogenicity prediction to genetic variants that affect RNA splicing. Karthik A. Jagadeesh, Joseph M. Paggi, James S. Ye, Peter D. Stenson, David N. Cooper, Jonathan A. Bernstein, Gill Bejerano

Xist lncRNA forms silencing granules that induce heterochromatin formation and repressive complexes recruitment by phase separation. Andrea Cerase, Alexandros Armaos, Fernando Cid-Samper, Phil Avner, Gian Gaetano Tartaglia

Ensemble Feature Selection and Meta-Analysis of Cancer miRNA Biomarkers. Alejandro Lopez-Rincon, Marlet Martinez-Archundia, Gustavo Ulises Martinez-Ruiz, Alberto Tond

Pan-cancer systematic identification of lncRNAs associated with cancer prognosis. Matthew Ung, Evelien Schaafsma, Daniel Mattox, George Wang, Chao Cheng

Cooption of antagonistic RNA-binding proteins establishes cell hierarchy in Drosophila neuro-developmental tumors. Sara Genovese, Raphael Clement, Cassandra Gaultier, Florence Besse, Karine Narbonne-Reveau, Fabrice Daian, Sophie Foppolo, Nuno Miguel Luis, Cédric Maurange

The mirtron miR-1010 functions in concert with its host gene SKIP to maintain synaptic homeostasis. Christopher Amourda, Timothy E Saunders

Chemically Accurate Relative Folding Stability of RNA Hairpins from Molecular Simulations. Louis G. Smith, Zhen Tan, Aleksandar Spasic, Debapratim Dutta, Leslie A. Salas-Estrada, Alan Grossfield, David Mathews

Cancer-associated mRNAs regulated by the Helix-Loop-Helix motif of human EIF3A. Marina Volegova, Jamie Cate

Transcriptome-wide profiling of mammalian spliceosome and branchpoints with iCLIP. Michael Briese, Nejc Haberman, Christopher Sibley, Anob Chakrabarti, Zhen Wang, Julian Konig, David Perera, Vihandha Wickramasinghe, Ashok Venkitaraman, Nicholas Luscombe, Christopher Smith, Tomaz Curk, Jernej Ule

Trans-splicing of mRNAs links gene transcription to translational control regulated by mTOR. Gemma Danks, Heloisa Galbiati, Martina Raasholm, Yamila N Torres Cleuren, Eivind Valen, Pavla Navratilova, Eric M Thompson

Brr2 is a splicing fidelity factor. Megan Mayerle, Christine Guthrie

Small RNAs from the plant pathogenic fungus Sclerotinia sclerotiorum highlight candidate host target genes associated with quantitative disease resistance. Mark Charles Derbyshire, Malick Mbengue, Marielle Barascud, Olivier Navaud, Sylvain Raffaele

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RNA preprints: W24/2018

Homeostasis of protein and mRNA concentrations in growing cells. Jie Lin, Ariel Amir

Transiently depleting RNPS1 leads to perdurable changes in alternative splicing. Jerôme Barbier, Alexandre Cloutier, Johanne Toutant, Mathieu Durand, Elvy Lapointe, Philippe Thibault, Benoit Chabot

cDeepbind: A context sensitive deep learning model of RNA-protein binding. Shreshth Gandhi, Leo J. Lee, Andrew Delong, David Duvenaud, Brendan Frey

Engineered resistance to Zika virus in transgenic Ae. aegypti expressing a polycistronic cluster of synthetic miRNAs. Anna Buchman, Stephanie Gamez, Ming Li, Igor Antoshechkin, hin-Hang Lee, Shin-Wei Wang, Chun-Hong Chen, Melissa J Klein, Jean-Bernard Duchmemin, Prasad N. Paradkar, Omar S Akbari

Effects of Short-time Exposure to Atrazine on miRNA Expression Profiles in the Gonad of Common Carp (Cyprinus Carpio). Fang Wang, Wen qian Yang, Jie wen Zhao, Yan qi Du, Jie zhong Chang

Impaired hematopoiesis and leukemia development in mice with a “knock-in” allele of U2af1(S34F). Dennis Liang Fei, Tao Zhen, Benjamin Durham, John Ferrarone, Tuo Zhang, Lisa Garrett, Akihide Yoshimi, Omar Abdel-Wahab, Robert Bradley, Paul Liu, Harold Varmus

Predict plant-derived xenomiRs from plant miRNA sequences using random forest and one-dimensional convolutional neural network models. Qi Zhao, Qian Mao, Zheng Zhao, Tongyi Dou, Zhiguo Wang, Xiaoyu Cui, Yuanning Liu, Xiaoya Fan

Elucidating the functional role of predicted miRNAs in post-transcriptional gene regulation along with symbiosis in Medicago truncatula. Ranjit Prasad Bahadur, Moumita Roy Chowdhury, Jolly Basak

Poor codon optimality is a signal to degrade transcripts with frameshifts. Miquel Angel Schikora Tamarit, Lucas Carey

Analyze Nucleic Acids Structures and Trajectories with Barnaba. Sandro Bottaro, Giovanni Bussi, Giovanni Pinamonti, Sabine Reisser, Wouter Boomsma, Kresten Lindorff-Larsen

LncRNA Spehd regulates hematopoietic stem cells and progenitors and is required for multilineage differentiation. M Joaquina Delás, Benjamin T Jackson, Tatjana Kovacevic, Silvia Vangelisti, Ester Munera Maravilla, Sophia A Wild, Eva Maria Stork, Nicolas Erard, Simon RV Knott, Gregory J Hannon

Testing the Red Queen hypothesis on de novo new genes – Run or die in the evolution of new microRNAs. Yixin Zhao, Hao Yang, Pei Lin, Zhongqi Liufu, Guang-An Lu, Jin Xu, Tian Tang, Haijun Wen, Chung-I Wu

Genome-wide identification of functional tRNA-derived fragments in Senescence-accelerated mouse prone 8 brain. Shuai Zhang, Hejian Li, Ling Zheng, Hong Li, Chengqiang Feng, Wensheng Zhang

RNA polymerase II clustering through CTD phase separation. Marc Boehning, Claire Dugast-Darzacq, Marija Rankovic, Anders S Hansen, Tae-Kyung Yu, Herve Marie-Nelly, David T McSwiggen, Goran Kokic, Gina M Dailey, Patrick Cramer, Xavier Darzacq, Markus Zweckstetter

Extracellular Vesicles promote host immunity during an M. tuberculosis infection through RNA Sensing. Jeff Schorey, Yong Cheng

Frequent translation of small open reading frames in evolutionary conserved lncRNA regions. Jorge Ruiz-Orera, M.Mar Alba

Mechanisms of gene death in the Red Queen race revealed by the analysis of de novo microRNAs. Guang-An Lu, Yixin Zhao, Ao Lan, Zhongqi Liufu, Haijun Wen, Tian Tang, Jin Xu, Chung-I Wu

The block spectrum of RNA pseudoknot structures. Thomas J. X. Li, Christina S. Burris, Christian M. Reidys

 

RNA preprints: W23/2018

Yeast PAF1 complex restricts the accumulation of RNA polymerase III and counters the replication stress on the transcribed genes. Pratibha Bhalla, Dipti Vinayak Vernekar, Ashutosh Shukla, Benoit Gilquin, Yohnn Coute, Purnima Bhargava

AQ-seq: Accurate quantification of microRNAs and their variants. Haedong Kim, Jimi Kim, Kijun Kim, Hyeshik Chang, Kwontae You, V. Narry Kim

Dynamics and spatial genomics of the nascent transcriptome in single mESCs by intron seqFISH. Sheel Shah, Yodai Takei, Wen Zhou, Eric Lubeck, Jina Yun, Noushin Koulena, Eric J. Liaw, Mina Amin, Long Cai

A long-non-coding RNA, LINC00473, confers the human adipose tissue thermogenic phenotype through enhanced cAMP responsiveness. Khanh-Van Tran, Cecilie Nandrup-Bus, Tiffany DeSouza, Ricardo Soares, Naja Zenius Jespersen, So Yun Min, Raziel Rojas-Rodriguez, Hanni Willenbrock, Therese Juhlin, Mai Charlotte Krogh Severinsen, Kimberly Malka, Bente Klarlund Pedersen, Timothy Fitzgibbons, Camilla Scheele, Silvia Corvera, Soeren Nielsen

Identifying miRNA-mRNA regulatory relationships in breast cancer with invariant causal prediction. Vu Viet Hoang Pham, Junpeng Zhang, Lin Liu, Buu Minh Thanh Truong, Taosheng Xu, Trung Tin Nguyen, Jiuyong Li, Thuc Duy Le

RNA tertiary structure energetics predicted by an ensemble model of the RNA double helix. Joseph David Yesselman, Sarah K Denny, Namita Bisaria, Daniel Herschlag, William J Greenleaf, Rhiju Das

Tristetraprolin/ZFP36 regulates the turnover of autoimmune-associated HLA-DQ mRNAs. Laura Pisapia, Russell Hamilton, Vito D’Agostino, Pasquale Barba, Maria Strazzullo, Alessandro Provenzani, Carmela Gianfrani, Giovanna Del Pozzo

Functional lability of RNA-dependent RNA polymerases in animals. Natalia Pinzón, Stéphanie Bertrand, Lucie Subirana, Isabelle Busseau, Hector Escrivá, Hervé Seitz

Pan-cancer analysis of RNA binding proteins (RBPs) reveals the involvement of the core pre-mRNA splicing and translation machinery in tumorigenesis. Bin Zhang, Kamesh Rajendra Babu, Chun You Lim, Zhi Hao Kwok, Jia Li, Siqin Zhou, Henry Yang, Yvonne Tay

Staphylococcus aureus Cas9 is a multiple-turnover enzyme. Paul Yourik, Ryan T Fuchs, Megumu Mabuchi, Jennifer L Curcuru, G. Brett Robb

Influence of miR-520e-mediated MAPK signaling pathway on HBV replication and regulation of hepatocellular carcinoma cells via targeting EphA2. Jing-hui Tian, Wen-dong Liu, Zhi-yong Zhang, Li-hua Tang, Dong Li, Zhao-ju Tian, Shao-wei Lin, Ying-jie Li

RNA Binding Motif Protein 48 is required for U12 splicing and maize endosperm differentiation. Fang Bai, Jacob Corll, Donya Shodja, Ruth Davenport, Guanqiao Feng, Janaki Mudunkothge, Christian J Brigolin, Federico Martin, Gertraud Spielbauer, Chi-Wah Tseung, Amy E Seibert, W. Brad Barbazuk, Shailesh Lal, A. Mark Settles

miR17~92 is essential for the survival of hematopoietic stem and progenitor cells by restraining pro-apoptotic BIM. Kerstin Brinkmann, Craig Hyland, Carolyn A de Graaf, Andreas Strasser, Warren S Alexander, Marco J Herold

Stem-loops direct precise processing of 3′ UTR-derived small RNA MicL. Taylor B. Updegrove, Andrew B Kouse, Katarzyna J Bandyra, Gisela Storz

Role of DCP1-DCP2 complex regulated by viral and host microRNAs in DNA virus infection. Yuechao Sun, Xiaobo Zhang

Deep sequencing of circulating exosomal microRNA allows non-invasive glioblastoma diagnosis. Saeideh Ebrahimkhani, Fatemeh Vafaee, Susannah Hallal, Heng Wei, Maggie Lee, Paul Young, Laveniya Satgunaseelan, Brindha Shivalingam, Catherine Suter, Michael Buckland, Kimberley Kaufman

Contrasting effects of aging on the expression of transposons, the piRNA machinery and mitochondrial transcripts in the Drosophila ovary. Alexandra A. Erwin, Justin P. Blumenstiel

A Novel Compound, ML336, Inhibits VEEV Replication by Interfering with Viral RNA Synthesis. Andrew M Skidmore, Robert S Adcock, Jasper Lee, Colleen Jonsson, Jennifer E Golden, Dong-Hoon Chung

Codon usage influences fitness through RNA toxicity. Pragya Mittal, James Brindle, Julie Stephen, Joshua B Plotkin, Grzegorz Kudla

The rainbow-spectrum of RNA secondary structures. Thomas J. X. Li, Christian M. Reidys

 

RNA preprints: W22/2018

Single-molecule imaging of mRNA localization and regulation during the integrated stress response. Johannes H Wilbertz, Franka Voigt, Ivana Horvathova, Gregory Roth, Yinxiu Zhan, Jeffrey Alan Chao

In situ quantification of individual mRNA transcripts in melanocytes discloses gene regulation of relevance to speciation. Chi-Chih Wu, Axel Klaesson, Julia Buskas, Petter Ranefall, Reza Mirzazadeh, Ola Söderberg, Jochen B. W. Wolf

Identifying lncRNA-mediated regulatory modules via ChIA-PET network analysis. Denise Anna Thiel, Nataša Djurdjevac Conrad, Ria X Peschutter, Heike Siebert, Annalisa Marsico

UPA-Seq: Prediction of Functional LncRNAs Using Differential Sensitivity to UV Crosslinking. Taiwa Komatsu, Mari Mito, Koichi Fujii, Shintaro Iwasaki, Shinichi Nakagawa

Imaging of single mRNA translation repression reveals diverse interactions with mRNP granules. Stephanie L Moon, Tatsuya Morisaki, Anthony Khong, Kenneth Lyon, Roy Parker, Timothy J Stasevich

Coarse-grained modeling for structure, stability and flexibility of double stranded RNAs in salt solutions. Lei Jin, Ya-Zhou Shi, Chen-Jie Feng, Ya-Lan Tan

Unbiased dynamic characterization of RNA-protein interactions by OOPS. Rayner M. L. Queiroz, Tom Smith, Eneko Villanueva, Mie Monti, Mariavittoria Pizzinga, Maria Marti-Solano, Dan-Mircea Mirea, Manasa Ramakrishna, Robert F. Harvey, Veronica Dezi, Sven Degroeve, Lennart Martens, Gavin H. Thomas, Anne E. Willis, Kathryn S. Lilley

Endogenous miRNA sponges mediate the generation of oscillatory dynamics for a non-coding RNA network. Andrew Dhawan, Adrian L. Harris, Francesca M Buffa, Jacob G Scott

The Human RNA-Binding Proteome and Its Dynamics During Arsenite-Induced Translational Arrest. Jakob Trendel, Thomas Schwarzl, Ananth Prakash, Alex Bateman, Matthias W Hentze, Jeroen Krijgsveld

De novo computational RNA modeling into cryoEM maps of large ribonucleoprotein complexes. Kalli Kappel, Shiheng Liu, Kevin P. Larsen, Georgios Skiniotis, Elisabetta Viani Puglisi, Joseph D. Puglisi, Z. Hong Zhou, Rui Zhao, Rhiju Das

Characterization and identification of long non-coding RNAs based on feature relationship. Guangyu Wang, Hongyan Yin, Boyang Li, Chunlei Yu, Fan Wang, Xingjian Xu, Jiabao Cao, Yiming Bao, Liguo Wang, Amir Abbasi, Vladimir Bajic, Lina Ma, Zhang Zhang

Purification of Cross-linked RNA-Protein Complexes by Phenol-Toluol Extraction. Erika C Urdaneta, Carlos H Vieira-Vieira, Timon Hick, Hans-Herrmann Wessels, Davide Figini, Rebecca Moschall, Jan Medenbach, Uwe Ohler, Sander Granneman, Matthias Selbach, Benedikt M Beckmann

Autonomous functionality of an upstream open reading frame in polycistronic mammalian mRNAs. Shohei Kitano, Gabriel Pratt, Keizo Takao, Yasunori Aizawa

Detection of cellular microRNAs with programmable DNA nanoswitches. Arun Richard Chandrasekaran, Molly MacIsaac, Paromita Dey, Oksana Levchenko, Lifeng Zhou, Madeline Andres, Bijan K Dey, Ken Halvorsen

xMD-miRNA-seq to generate near in vivo miRNA expression estimates in colon epithelial cells. Avi Z Rosenberg, Carrie Wright, Karen Fox-Talbot, Anandita Rajpurohit, Courtney Williams, Corey Porter, Olga Kovbasnjuk, Matthew N McCall, Joo Heon Shin, Marc K. Halushka

Novel RNA aptamers targeting gastrointestinal cancer biomarkers CEA, CA50 and CA72-4 with superior affinity and specificity. Qing Pan, Carmen O.K. Law, Mingo M.H. Yung, K.C. Han, Yuen Lam Pon, Terrence chi kong Lau

Prioritizing bona fide bacterial small RNAs with machine learning classifiers. Erik JJ Eppenhof, Lourdes Peña-Castillo​

 

RNA preprints: W21/2018

EternaBrain: Automated RNA design through move sets from an Internet-scale RNA videogame. Rohan Koodli, Benjamin Keep, Katherine R Coppess, Fernando Portela, Eterna Players, Rhiju Das

RNA components of the spliceosome regulate tissue- and cancer-specific alternative splicing. Heidi Dvinge, Jamie Guenthoer, Peggy L Porter, Robert K Bradley

N4-acetylcytidine and 5-formylcytidine are present in Saccharomyces cerevisiae mRNAs. Mehmet Tardu, Qishan Lin, Kristin Koutmou

TLR3-TRIF pathway activation by Neospora caninum RNA enhances infection control. Vanessa dos Santos Miranda, Flávia Batista Ferreira França, Mylla Spirandelli da Costa, Vanessa Resende Souza Silva, Caroline Martins Mota, Patricio da Silva Cardoso Barros, Kleber Simonio Parreira, Fernanda Maria Santiago, Jose Roberto Mineo, Tiago WP Mineo

Genetic compensation is triggered by mutant mRNA degradation. Mohamed El-Brolosy, Andrea Rossi, Zacharias Kontarakis, Carsten Kuenne, Stefan Guenther, Nana Fukuda, Carter Takacs, Shih-Lei Lai, Ryuichi Fukuda, Claudia Gerri, Khrievono Kikhi, Antonio Giraldez, Didier Y.R. Stainier

MicroRNA-184 Is Induced By Store-Operated Calcium Entry And Regulates Early Keratinocyte Differentiation. Adam Richardson, Andrew Powell, Darren W. Sexton, Jason L. Parsons, Nicholas J. Reynolds, Kehinde Ross

A Deep Learning Approach for Learning Intrinsic Protein-RNA Binding Preferences. Ilan Ben-Bassat, Benny Chor, Yaron Orenstein

MicroRNA-196a is regulated by ER and is a prognostic biomarker in ER+ Breast Cancer. Michael Milevskiy, Udai Gujral, Carolina Del Lama Marques, Andrew Stone, Korinne Northwood, Lez Burke, Julia Gee, Kenneth Nephew, Susan Clark, Melissa Brown

The RNA demethylase FTO targets m6Am in snRNA to establish distinct methyl isoforms that influence splicing. Jan Mauer, Miriam Sindelar, Théo Guez, Jean-Jacques Vasseur, Andrea Rentmeister, Steven S Gross, Livio Pellizzoni, Françoise Debart, Hani Goodarzi, Samie R Jaffrey

The 5′ untranslated region of the EFG1 transcript promotes its translation to regulate hyphal morphogenesis in Candida albicans. Prashant R. Desai, Klaus Lengeler, Mario Kapitan, Silas M. Janßen, Paula Alepuz, Ilse D. Jacobsen, Joachim F. Ernst

miR-21-5p and miR-30a-5p are identical in human and bovine, have similar isomiR distribution, and cannot be used to identify xenomiR uptake from cow milk. Bastian Fromm, Juan Pablo Tosar, Yin Lu, Marc K Halushka, Kenneth W Witwer

Long noncoding RNA ANRIL supports proliferation of adult T-cell leukemia cells through cooperation with EZH2. Zaowen Song, Wencai Wu, Mengyun Chen, Wenzhao Cheng, Juntao Yu, Jinyong Fang, Lingling Xu, Jun-ichirou Yasunaga, Masao Matsuoka, Tiejun Zhao

Olive mild mosaic virus coat protein and p6 are suppressors of RNA silencing and their silencing confers resistance against OMMV. Carla Varanda, Patrick Materatski, Maria Doroteia Campos, Maria Ivone Clara, Gustavo Nolasco, Maria Rosário Félix

CD95L mRNA is toxic to cells. William Putzbach, Ashley Haluck-Kangas, Quan Q Gao, Aishe A Sarshad, Elizabeth T Bartom, Austin Stults, Abdul S Qadir, Markus Hafner, Marcus E Peter

Transcription factor TAp73 and miRNA-449 cooperate in multiciliogenesis. Merit Wildung, Tilman Uli Esser, Katie Baker Grausam, Cornelia Wiedwald, Li Li, Jessica Lynn Simcox Zylla, Ann-Kathrin Günther, Magdalena Wienken, Evrim Ercetin, Felix Bremmer, Orr Shomroni, Stefan Andreas, Haotian Zhao, Muriel Lizé

Non-coding AUG circRNAs constitute an abundant and conserved subclass of circles. Lotte Victoria Winther Stagsted, Katrine Mandrup Nielsen, Iben Daugaard, Thomas Birkballe Hansen

Base-pair Ambiguity and the Kinetics of RNA Folding: a Hypothesis-Driven Statistical Analysis. Guangyao Zhou, Jackson Loper, Stuart Geman

Time Dependent Stochastic mRNA and Protein Synthesis in Piecewise-deterministic Models of Gene Networks. Guilherme Innocentini, Arran Hodgkinson, Ovidiu Radulescu

Let-7i-5p regulation of cell morphology and migration through distinct signaling pathways in normal and pathogenic fibroblasts from urethra. Kaile Zhang, Jun Chen, Shukui Zhou, Ranxin Yang, Ying Wang, Qiang Fu, Rong Chen, Xiaolan Fang

Multiplexed Primer Extension Sequencing Enables High Precision Detection of Rare Splice Isoforms. Hansen Xu, Benjamin J Fair, Zach Dwyer, Michael Gildea, Jeffrey A Pleiss

D-amino acid-mediated translation arrest is modulated by the identity of the incoming aminoacyl-tRNA. Rachel C. Fleisher, Virginia W. Cornish, Ruben L. Gonzalez Jr.