RNA preprints: W45/2018

Slow transcriptional elongation causes embryonic lethality and perturbs kinetic coupling of long neural genes. Magdalena M Maslon, Ulrich Braunschweig, Stuart Aitken, Abigail R Mann, Fiona Kilanowski, Chris J Hunter, Benjamin J Blencowe, Alberto R Kornblihtt, Ian R Adams, Javier F. Caceres

The spermidine acetyltransferase SpeG regulates transcription of the small RNA RprA. Linda I. Hu, Ekaterina V. Filippova, Joseph Dang, Sergii Pshenychnyi, Jiapeng Ruan, Olga Kiryukhina, Wayne F. Anderson, Misty L. Kuhn, Alan Wolfe

Timing Polymerase Pausing with TV-PRO-seq. Jie Zhang, Massimo Cavallaro, Daniel Hebenstreit

Limited differential expression of miRNAs and other small RNAs in LPS-stimulated human monocytes. Daniel Lu, Tracy Yamawaki, Hong Zhou, Wen-Yu Chou, Mark Chhoa, Edwin Lamas, Sabine S Escobar, Heather A Arnett, Huanying Ge, Songli Wang, Chi-Ming Li

Statistical Mechanical Prediction of Ligand Perturbation to RNA Secondary Structure and Application to the SAM-I Riboswitch. Osama Alaidi, Fareed Aboul-ela

Nonsynonymous A-to-I RNA editing contributes to burden of deleterious missense variants in healthy individuals. Te-Lun Mai, Trees-Juen Chuang

FMRP association with and regulation of Fragile X granules exhibit circuit-dependent requirements for the KH2 RNA binding domain. Ellen C Gingrich, Katherine A Shepard, Molly E Mitchell, Kirsty Sawicka, Jennifer C Darnell, Michael R Akins

Pan-cancer analysis on microRNA-mediated gene activation. Hua Tan, Shan Huang, Zhigang Zhang, Xiaohua Qian, Peiqing Sun, Xiaobo Zhou

Differential phase partition of a PICS complex is required for piRNA processing and chromosome segregation in C. elegans. Chenming Zeng, Chenchun Weng, Xiaoyang Wang, Yong-Hong Yan, Wen-Jun Li, Demin Xu, Minjie Hong, Shanhui Liao, Xuezhu Feng, Meng-Qiu Dong, Chao Xu, Shouhong Guang

Photoperiod-dependent expression of MicroRNA in Drosophila. Mirko Pegoraro, Eran Tauber

ARF5/MONOPTEROS directly regulates miR390 expression in the Arabidopsis thaliana primary root meristem. Mouli Ghosh Dastidar, Andrea Scarpa, Ira Maegele, Paola Ruiz Duarte, Patrick von Born, Lotte Bald, Virginie Jouannet, Alexis Maizel

Axonal localization of the Fragile X family of RNA binding proteins is conserved across mammals. Katherine A Shepard, Lulu I T. Korsak, Michael Akins

PETISCO is a novel protein complex required for 21U RNA biogenesis and embryonic viability. Ricardo J Cordeiro Rodrigues, Antonio Miguel de Jesus Domingues, Svenja Hellmann, Sabrina Dietz, Bruno de Albuquerque, Christian Renz, Helle D. Ulrich, Falk Butter, Rene Kettin

Evidence of a noncoding transcript of the RIPK2 gene overexpressed in head and neck tumor. Eloiza Helena Tajara, Ulises MM Villagra, Bianca R da Cunha, Giovana M Polachini, Tiago Henrique, Carlos H. T. P. da Silva, Olavo A Feitosa, Erica E. Erica E. Fukuyama, Rossana V.M. López, Emmanuel Dias-Neto, Fabio D. Nunes, Patricia Severino

Single cell transcriptomes reveal characteristics of miRNA in gene expression noise reduction. Tao Hu, Lei Wei, Shuailin Li, Tianrun Cheng, Xuegong Zhang, Xiaowo Wang

TriPepSVM – de novo prediction of RNA-binding proteins based on short amino acid motifs. Annkatrin Bressin, Roman Schulte-Sasse, Davide Figini, Erika C. Urdaneta, Benedikt M. Beckmann, Annalisa Marsico

A unique No-Go Decay cleavage in mRNA exit-tunnel of ribosome produces 5′-OH ends phosphorylated by Rlg1. Albertas Navickas, Sebastien Chamois, Renette Saint-Fort, Julien Henri, Claire Torchet, Lionel Benard

RNA is a critical element for the sizing and the composition of phase-separated RNA-protein condensates. Marina Garcia-Jove Navarro, Shunnichi Kashida, Racha Chouaib, Sylvie Souquere, Gerard Pierron, Dominique Weil, Zoher Gueroui

PRMT1-mediated methylation of the Large Drosha Complex regulates microRNA biogenesis. Tiziana Bonaldi, Valeria Spadotto, Roberto Giambruno, Enrico Massignani, Marija Mihailovich, Francesca Patuzzo, Francesco Ghini, Francesco Nicassio

Identification of potential microRNAs associated with Herpesvirus family based on bioinformatic analysis. Kevin Lamkiewicz, Emanuel Barth, Manja Marz, Bashar Ibrahim

Nanopore native RNA sequencing of a human poly(A) transcriptome. Rachael E Workman, Alison Tang, Paul S. Tang, Miten Jain, John R Tyson, Philip C Zuzarte, Timothy Gilpatrick, Roham Razaghi, Joshua Quick, Norah Sadowski, Nadine Holmes, Jaqueline Goes de Jesus, Karen Jones, Terrance P Snutch, Nicholas James Loman, Benedict Paten, Matthew W Loose, Jared T Simpson, Hugh E. Olsen, Angela N Brooks, Mark Akeson, Winston Timp

Novel autoregulatory cases of alternative splicing coupled with nonsense-mediated mRNA decay. Dmitri Pervouchine, Iaroslav Popov, Andy Berry, Beatrice Borsari, Adam Frankish, Roderic Guigo

Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1,2 of Drosophila helicase Maleless. Pravin Kumar Ankush Jagtap, Marisa Mueller, Pawel Masiewicz, Soeren von Buelow, Nele Merret Hollmann, Bernd Simon, Andreas W Thomae, Peter B Becker, Janosch Hennig

Core components of endosomal mRNA transport are evolutionarily conserved in fungi. Jessica Mueller, Thomas Pohlmann, Michael Feldbruegge

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