RNA preprints: W12/2019

The lncRNA NEAT1_1 is dispensable for normal tissue homeostasis and cancer cell growth. Carmen Adriaens, Florian Rambow, Greet Bervoets, Toomas Silla, Mari Mito, Tomoki Chiba, Asahara Hiroshi, Tetsuro Hirose, Shinichi Nakagawa, Torben Heick Jensen, Jean-Christophe Marine

DNA methylation, microRNA expression profiles and their relationships with transcriptome in grass-fed and grain-fed Angus Cattle rumen tissue. Yaokun Li, José A. Carrillo, Yi Ding, Yanghua He, Chunping Zhao, Jianan Liu, Linsen Zan, Jiuzhou Song

Post-transcriptional mechanisms distinguish human and chimp forebrain progenitor cells. Daniela A Grassi, Per Ludvik Brattås, Jeovanis G Valdés, Melinda Rezeli, Marie E Jönsson, Sara Nolbrant, Malin Parmar, György Marko-Varga, Johan Jakobsson

ITGA2 is a target of miR-206 promoting cancer stemness and lung metastasis through enhanced ACLY and CCND1 expression in triple negative breast cancer. Valery Adorno-Cruz, Andrew D. Hoffmann, Xia Liu, Brian Wray, Ruth A. Keri, Huiping Liu

Functional RNA Structures in the 3’UTR of Tick-Borne, Insect-Specific and No-Known-Vector Flaviviruses. Roman Ochsenreiter, Ivo L. Hofacker, Michael T. Wolfinger

A type III CRISPR ancillary ribonuclease degrades its cyclic oligoadenylate activator. Januka S. Athukoralage, Shirley Graham, Sabine Grüschow, Christophe Rouillon, Malcolm F. White

Assessing the role of long-noncoding RNA in nucleus accumbens in subjects with alcohol dependence. Gowon O. McMichael, John Drake, Eric Sean Vornholt, Kellen Cresswell, Vernell Williamson, Chris Chatzinakos, Mohammed Mamdani, Siddharth Hariharan, Kenneth S. Kendler, Michael F. Miles, Gursharan Kalsi, Brien P. Riley, Mikhail Dozmorov, Silviu-Alin Bacanu, Vladimir I. Vladimirov

Identification and classification of hubs in miRNA target gene networks in human neural stem/progenitor cells following Japanese encephalitis virus infection. Sriparna Mukherjee, Irshad Akbar, Reshma Bhagat, Bibhabasu Hazra, Arindam Bhattacharyya, Pankaj Seth, Dipanjan Roy, Anirban Basu

A regulatory RNA is associated to invasive meningococcal disease in Europe. Jens Karlsson, Hannes Eichner, Susanne Jacobsson, Edmund Loh

Tissue-specific MicroRNA Expression Alters Cancer Susceptibility Conferred by a TP53 Noncoding Variant. Qipan Deng, Hui Hu, Xinfang Yu, Shuanglin Liu, Lei Wang, Weiqun Chen, Chi Zhang, Zhaoyang Zeng, Ya Cao, Ling Li, Mingzhi Zhang, Steven Rosenfeld, Shideng Bao, Eric Hsi, Ken H Young, Zhongxin Lu, Yong Li

Phenotypical microRNA screen reveals a noncanonical role of CDK2 in regulating neutrophil migration. A.Y. Hsu, D. Wang, S. Liu, J. Lu, R. Syahirah, D.A. Bennin, A. Huttenlocher, D.M. Umulis, J. Wan, Q. Deng

Krüppel-like factor 2- induced microRNAs: implications for treatment of pulmonary hypertension. Hebah Sindi, Giusy Russomanno, Kyeong Beom Jo, Vahitha B. Abdul-Salam, Basma Qazi Chaudhry, Alexander J. Ainscough, Robert Szulcek, Harm Jan Bogaard, Claire C. Morgan, Soni Pullamsetti, Mai Alzaydi, Christopher J. Rhodes, Christina A. Eichstaedt, Ekkehard Grünig, Martin R. Wilkins, Beata Wojciak-Stothard

An Exon Skipping Screen Identifies Antitumor Drugs That Are Potent Modulators of Pre-mRNA Splicing, Suggesting New Therapeutic Applications. Yihui Shi, Walter Bray, Alexander J. Smith, Wei Zhou, Joy Calaoagan, Chandraiah Lagisetti, Lidia Sambucetti, Phillip Crews, R. Scott Lokey, Thomas R. Webb

miRspongeR: an R/Bioconductor package for the identification and analysis of miRNA sponge interaction networks and modules. Junpeng Zhang, Lin Liu, Taosheng Xu, Yong Xie, Chunwen Zhao, Jiuyong Li, Thuc Duy Le

Profiling Gene Specific Changes to RNA Editome in Preeclampsia. Saam Hasan, Shahriyar Mahdi Robbani, Tamanna Afroze, Gias U Ahsan, Muhammad Maqsud Hossain

microRNA mir-598-3p mediates susceptibility to stress-enhancement of remote fear memory. Meghan E Jones, Stephanie E. Sillivan, Sarah Jamieson, Gavin Rumbaugh, Courtney A. Miller

High-throughput RNA sequencing from paired lesional- and non-lesional skin reveals major alterations in the psoriasis circRNAome. Liviu-Ionut Moldovan, Thomas Birkballe Hansen, Morten Trillingsgaard Venø, Trine Line Hauge Okholm, Thomas Levin Andersen, Henrik Hager, Lars Iversen, Jørgen Kjems, Claus Johansen, Lasse Sommer Kristensen

Srrm234, but not canonical SR and hnRNP proteins drive inclusion of Dscam exon 9 variable exons. Pinar Ustaoglu, Irmgard U. Haussmann, Hongzhi Liao, Antonio Torres-Mendez, Roland Arnold, Manuel Irimia, Matthias Soller

Levels of sdRNAs in cytoplasm and their association with ribosomes are dependent upon stress conditions but independent from snoRNA expression. Anna M. Mleczko, Piotr Machtel, M. Walkowiak, A. Wasilewska, K. Bąkowska-Żywicka

3.1Å structure of yeast RNA polymerase II elongation complex stalled at a cyclobutane pyrimidine dimer lesion solved using streptavidin affinity grids. Indrajit Lahiri, Jun Xu, Bong Gyoon Han, Juntaek Oh, Dong Wang, Frank DiMaio, Andres E Leschziner

Circular RNA profiling in the oocyte and cumulus cells reveals that circARMC4 is essential for porcine oocyte maturation. Zubing Cao, Di Gao, Tengteng Xu, Ling Zhang, Xu Tong, Dandan Zhang, Yiqing Wang, Wei Ning, Xin Qi, Yangyang Ma, Kaiyuan Ji, Tong Yu, Yunsheng Li, Yunhai Zhang

Structure-guided enhancement of selectivity of chemical probe inhibitors targeting bacterial seryl-tRNA synthetase. Ricky Cain, Ramya Salimraj, Avinash S. Punekar, Dom Bellini, Colin W. G. Fishwick, Lloyd Czaplewski, David J. Scott, Gemma Harris, Christopher G. Dowson, Adrian J. Lloyd, David I. Roper

Musashi binding elements in Zika and related Flavivirus 3’UTRs: A comparative study in silico. Adriano de Bernardi Schneider, Michael T. Wolfinger

Quantitation of cis-translational control by general mRNA sequence features in five eukaryotes. Jingyi Jessica Li, Guo-Liang Chew, Mark D Biggin

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